hiv integrase — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T11566	HIV-1 integrase inhibitor		Others
	Hiv-1 integrase inhibitor is an effective anti-HIV drug.		Others
T11568	HIV-1 integrase inhibitor 4		Others
	HIV-1 integrase inhibitor 4 is an HIV-1 integrase strand transfer (INST) inhibitor (IC50: 3.7 nM).		Others
T11567	HIV-1 integrase inhibitor 3		Others
	HIV-1 integrase inhibitor 3 is an HIV-1 integrase strand transfer (INST) inhibitor (IC50: 2.7 nM).		Others
T11565	HIV-1 integrase inhibitor 7		Others
	HIV-1 integrase inhibitor 7 is a potent HIV-1 integrase inhibitor (IC50: 33.3 nM).		Others
T60742	HIV-1 integrase inhibitor 8		HIV Protease
	HIV-1 integrase inhibitor 8 is an inhibitor of HIV-1 integrase. Integration is a required step in HIV replication [1].		HIV Protease
T4182	Lavendustin B		Tyrosinase , transporter , HIV Protease
	Lavendustin B is a Tyrosine Kinase Inhibitor and an inhibitor of HIV-1 integrase (IN) interaction with its cognate cellular cofactor, lens epithelium-derived growth factor (LEDGF/p75).		Tyrosinase , transporter , HIV Protease
T4493	Bictegravir	GS-9883	HIV Protease
	Bictegravir (GS-9883) is a potent inhibitor of HIV-1 integrase (IC50: 7.5 nM).		HIV Protease
T2239L	Raltegravir	MK-0518	HIV Protease , Integrase
	Raltegravir (MK-0518) is a pyrrolidinone derivative and HIV INTEGRASE INHIBITOR that is used in combination with other ANTI-HIV AGENTS for the treatment of HIV INFECTION.		HIV Protease , Integrase
T0753	Salicylanilide	WR10019,2-Hydroxybenzanilide	HIV Protease , Reverse Transcriptase
	Salicylanilide (2-Hydroxybenzanilide)s are a group of compounds with antiviral potency, antibacterial and antifungal activities.		HIV Protease , Reverse Transcriptase
T6420	BMS-707035		HIV Protease
	BMS-707035 is a specific HIV-I integrase (IN) inhibitor with IC50 of 15 nM. Phase 2.		HIV Protease
T2332	Elvitegravir	GS-9137,EVG,D06677,JTK-303	HIV Protease
	Elvitegravir (JTK-303) is a Human Immunodeficiency Virus Integrase Strand Transfer Inhibitor. The mechanism of action of elvitegravir is as an HIV Integrase Inhibitor, and Cytochrome P450 2C9 Inducer.		HIV Protease
T2239	Raltegravir potassium	MK 0518 potassium salt,Raltegravir potassium salt	HIV Protease , Integrase
	Raltegravir potassium (MK 0518 potassium salt) salt(MK0518 potassium salt) is a potent integrase (IN) inhibitor, used to treat HIV infection.		HIV Protease , Integrase
T6198	Dolutegravir	S/GSK1349572,GSK1349572	HIV Protease
	Dolutegravir (GSK1349572) (IC50=2.7 nM), a two-metal-binding HIV integrase inhibitor, exhibits medium activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H.		HIV Protease
T62156	HIV-1 integrase inhibitor 9
	HIV-1 integrase inhibitor 9 (compound 8a) is a potent inhibitor of HIV-1 RNase H (IC50: 12.3 μM) and has antiviral effects.
T72162	HIV-1 integrase inhibitor 10
	HIV-1 Integrase Inhibitor 10, an orally active allosteric integrase inhibitor (ALLINI), effectively inhibits the NLRepRluc virus's viral outgrowth in MT-2 cells, exhibiting EC50 values of 3-5 nM. This compound is utilize...
T2329	Dolutegravir sodium	GSK1349572,GSK-1349572A	HIV Protease
	Dolutegravir sodium (GSK-1349572A) salt(DTG; GSK1349572) is an HIV integrase inhibitor(IC50: 2.7 nM), modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H.		HIV Protease
T9854	HIV-1 inhibitor-6	3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-	HIV Protease
	HIV-1 inhibitor-6 (3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-) is a potent HIV-1 pre-mRNA selective splicing inhibitor that blocks HIV replication.		HIV Protease
T6S2391	L-Chicoric Acid	(-)-Chicoric acid,trans-Caffeoyltartaric acid,Chicoric acid,dicaffeoyltartaric acid	Others , HIV Protease
	L-Chicoric Acid (trans-Caffeoyltartaric acid) has been shown to inhibit hyaluronidase and HIV-1 integrase, and to possess phagoeytosis stimulatory activity in vitro and in vivo and antiviral acitivy. L-Chicoric acid may ...		Others , HIV Protease
T15483	LEDGIN6	HIV-1 integrase inhibitor 2	Others
	HIV-1 integrase inhibitor 2 is used for the treatment of human immunodeficiency virus (HIV) infection.		Others
T6098	Cabotegravir	GSK744,GSK-1265744,S/GSK1265744	HIV Protease
	Cabotegravir (S/GSK1265744) (GSK744, GSK1265744) is a long-acting HIV integrase inhibitor and inhibits the HIV-1 integrase catalyzed strand transfer reaction (IC50: 3.0 nM).		HIV Protease